diff --git a/scripts/west_commands/runners/esp32.py b/scripts/west_commands/runners/esp32.py
index 64349a20bfc..375aa1e63f1 100644
--- a/scripts/west_commands/runners/esp32.py
+++ b/scripts/west_commands/runners/esp32.py
@@ -8,6 +8,8 @@ from os import path
 
 from runners.core import ZephyrBinaryRunner, RunnerCaps
 
+import sys
+
 
 class Esp32BinaryRunner(ZephyrBinaryRunner):
     '''Runner front-end for espidf.'''
@@ -86,6 +88,11 @@ class Esp32BinaryRunner(ZephyrBinaryRunner):
                      '--flash_freq', self.flash_freq,
                      '--flash_size', self.flash_size]
 
+        # Execute Python interpreter if calling a Python script
+        if self.espidf.lower().endswith(".py") and sys.executable:
+            cmd_convert.insert(0, sys.executable)
+            cmd_flash.insert(0, sys.executable)
+
         if self.bootloader_bin:
             cmd_flash.extend(['0x1000', self.bootloader_bin])
             cmd_flash.extend(['0x8000', self.partition_table_bin])