diff --git a/modules/trusted-firmware-m/Kconfig.tfm b/modules/trusted-firmware-m/Kconfig.tfm
index c1a1c82186a..711961714a0 100644
--- a/modules/trusted-firmware-m/Kconfig.tfm
+++ b/modules/trusted-firmware-m/Kconfig.tfm
@@ -12,7 +12,7 @@ config TFM_BOARD
 	default "nordic_nrf/nrf9160dk_nrf9160" if BOARD_NRF9160DK_NRF9160NS
 	default "nordic_nrf/nrf5340dk_nrf5340_cpuapp" if BOARD_NRF5340DK_NRF5340_CPUAPPNS
 	default "nxp/lpcxpresso55s69" if BOARD_LPCXPRESSO55S69_CPU0
-	default "mps2/an521" if BOARD_MPS2_AN521
+	default "mps2/an521" if BOARD_MPS2_AN521_CPU0_NS
 	default "stm/nucleo_l552ze_q" if BOARD_NUCLEO_L552ZE_Q
 	default "stm/stm32l562e_dk" if BOARD_STM32L562E_DK
 	default "musca_b1/sse_200" if BOARD_MUSCA_B1