diff --git a/drivers/serial/Kconfig.sam0 b/drivers/serial/Kconfig.sam0
index 8311c7caa11..eb6eaed670f 100644
--- a/drivers/serial/Kconfig.sam0
+++ b/drivers/serial/Kconfig.sam0
@@ -9,8 +9,12 @@ config UART_SAM0
 	depends on DT_HAS_ATMEL_SAM0_UART_ENABLED
 	select SERIAL_HAS_DRIVER
 	select SERIAL_SUPPORT_INTERRUPT
-	# the ASYNC implementation requires a DMA controller
 	select SERIAL_SUPPORT_ASYNC if DT_HAS_ATMEL_SAM0_DMAC_ENABLED
-	select DMA if UART_ASYNC_API
 	help
 	  This option enables the SERCOMx USART driver for Atmel SAM0 MCUs.
+
+config UART_SAM0_ASYNC
+	bool "Async UART support for Atmel SAM0 series."
+	depends on DMA_SAM0
+	depends on UART_SAM0
+	depends on UART_ASYNC_API
diff --git a/drivers/serial/uart_sam0.c b/drivers/serial/uart_sam0.c
index 4f4407bdca9..d3953fc6313 100644
--- a/drivers/serial/uart_sam0.c
+++ b/drivers/serial/uart_sam0.c
@@ -43,10 +43,10 @@ struct uart_sam0_dev_cfg {
 	uint32_t pm_apbcmask;
 	uint16_t gclk_clkctrl_id;
 #endif
-#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_ASYNC_API
+#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_SAM0_ASYNC
 	void (*irq_config_func)(const struct device *dev);
 #endif
-#if CONFIG_UART_ASYNC_API
+#if CONFIG_UART_SAM0_ASYNC
 	const struct device *dma_dev;
 	uint8_t tx_dma_request;
 	uint8_t tx_dma_channel;
@@ -64,7 +64,7 @@ struct uart_sam0_dev_data {
 	void *cb_data;
 	uint8_t txc_cache;
 #endif
-#if CONFIG_UART_ASYNC_API
+#if CONFIG_UART_SAM0_ASYNC
 	const struct device *dev;
 	const struct uart_sam0_dev_cfg *cfg;
 
@@ -126,7 +126,7 @@ static int uart_sam0_set_baudrate(SercomUsart *const usart, uint32_t baudrate,
 }
 
 
-#if CONFIG_UART_ASYNC_API
+#if CONFIG_UART_SAM0_ASYNC
 
 static void uart_sam0_dma_tx_done(const struct device *dma_dev, void *arg,
 				  uint32_t id, int error_code)
@@ -565,11 +565,11 @@ static int uart_sam0_init(const struct device *dev)
 	}
 	dev_data->config_cache.baudrate = cfg->baudrate;
 
-#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_ASYNC_API
+#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_SAM0_ASYNC
 	cfg->irq_config_func(dev);
 #endif
 
-#ifdef CONFIG_UART_ASYNC_API
+#ifdef CONFIG_UART_SAM0_ASYNC
 	dev_data->dev = dev;
 	dev_data->cfg = cfg;
 	if (!device_is_ready(cfg->dma_dev)) {
@@ -705,7 +705,7 @@ static int uart_sam0_err_check(const struct device *dev)
 	return err;
 }
 
-#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_ASYNC_API
+#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_SAM0_ASYNC
 
 static void uart_sam0_isr(const struct device *dev)
 {
@@ -717,7 +717,7 @@ static void uart_sam0_isr(const struct device *dev)
 	}
 #endif
 
-#if CONFIG_UART_ASYNC_API
+#if CONFIG_UART_SAM0_ASYNC
 	const struct uart_sam0_dev_cfg *const cfg = dev->config;
 	SercomUsart * const regs = cfg->regs;
 
@@ -936,14 +936,14 @@ static void uart_sam0_irq_callback_set(const struct device *dev,
 	dev_data->cb = cb;
 	dev_data->cb_data = cb_data;
 
-#if defined(CONFIG_UART_EXCLUSIVE_API_CALLBACKS)
+#if defined(CONFIG_UART_SAM0_ASYNC) && defined(CONFIG_UART_EXCLUSIVE_API_CALLBACKS)
 	dev_data->async_cb = NULL;
 	dev_data->async_cb_data = NULL;
 #endif
 }
 #endif
 
-#ifdef CONFIG_UART_ASYNC_API
+#ifdef CONFIG_UART_SAM0_ASYNC
 
 static int uart_sam0_callback_set(const struct device *dev,
 				  uart_callback_t callback,
@@ -1205,7 +1205,7 @@ static const struct uart_driver_api uart_sam0_driver_api = {
 	.irq_update = uart_sam0_irq_update,
 	.irq_callback_set = uart_sam0_irq_callback_set,
 #endif
-#if CONFIG_UART_ASYNC_API
+#if CONFIG_UART_SAM0_ASYNC
 	.callback_set = uart_sam0_callback_set,
 	.tx = uart_sam0_tx,
 	.tx_abort = uart_sam0_tx_abort,
@@ -1215,7 +1215,7 @@ static const struct uart_driver_api uart_sam0_driver_api = {
 #endif
 };
 
-#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_ASYNC_API
+#if CONFIG_UART_INTERRUPT_DRIVEN || CONFIG_UART_SAM0_ASYNC
 
 #define SAM0_UART_IRQ_CONNECT(n, m)					\
 	do {								\
@@ -1253,7 +1253,7 @@ static void uart_sam0_irq_config_##n(const struct device *dev)		\
 #define UART_SAM0_IRQ_HANDLER(n)
 #endif
 
-#if CONFIG_UART_ASYNC_API
+#if CONFIG_UART_SAM0_ASYNC
 #define UART_SAM0_DMA_CHANNELS(n)					\
 	.dma_dev = DEVICE_DT_GET(ATMEL_SAM0_DT_INST_DMA_CTLR(n, tx)),	\
 	.tx_dma_request = ATMEL_SAM0_DT_INST_DMA_TRIGSRC(n, tx),	\
diff --git a/tests/drivers/uart/uart_async_api/testcase.yaml b/tests/drivers/uart/uart_async_api/testcase.yaml
index 324c9a90831..9767f9a80ae 100644
--- a/tests/drivers/uart/uart_async_api/testcase.yaml
+++ b/tests/drivers/uart/uart_async_api/testcase.yaml
@@ -1,26 +1,8 @@
 common:
   platform_exclude:
-    - seeeduino_xiao
-    - serpente
-    - arduino_nano_33_iot
-    - atsamr21_xpro
-    - adafruit_itsybitsy_m4_express
-    - atsame54_xpro
-    - atsamc21n_xpro
-    - adafruit_trinket_m0
-    - arduino_nano_33_iot
-    - arduino_zero
-    - atsamd21_xpro
-    - adafruit_feather_m0_basic_proto
-    - adafruit_feather_m0_lora
-    - arduino_mkrzero
-    - atsaml21_xpro
-    - atsamr34_xpro
     - stamp_c3
     - wio_terminal
     - xiao_esp32c3
-    - atsamd20_xpro
-    - ev11l78a
   tags:
     - drivers
     - uart